Mayo Clinic

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Contributor: Minnesota Historical Society Press
Source: Minnesota 150 (F606 .R63 2007)
Mayo Clinic, Rochester

Mayo Clinic, Rochester, c.1930.

On May 31, 1819, a boy was born in a small village near Manchester, England. His father died when the boy was only seven, leaving his mother to raise him and his five siblings. She worked hard to provide a good education for her children; the boy was tutored in Latin and Greek and began studies in medicine and science with John Dalton, who would later be known as "the father of modern physical science" for his groundbreaking work in developing the atomic theory of matter.

The boy grew into a man, and at twenty-seven he left Manchester for the United States. He landed in New York and soon moved west, working as a pharmacist, a tailor, a census taker, a farmer, a newspaper publisher, a justice of the peace, a ferryboat operator, and a veterinarian before completing his medical training in Indiana in 1850 and moving to Minnesota four years later.

Thus begins the story of Dr. William Worrall Mayo, whose name is synonymous today with high-quality, compassionate health care. Dr. Mayo and his sons, William and Charles, helped put the north star state on the map when they founded their clinic in Rochester, Minnesota.

In 1861, William W. Mayo, then living in Le Sueur, Minnesota, volunteered for duty in the Union army, but his application for regimental surgeon was denied. Two years later, he was appointed the examining surgeon for an enrollment board based in Rochester that selected military recruits. In January 1864, William W. Mayo, his wife Louise—a skilled milliner who would later become her husband's medical assistant—and their children settled down in Rochester for good.

From the start, the Mayos' private practice was a family affair. Louise instructed her sons, Will and Charlie, in botany as they worked in the garden; their father taught them chemistry and anatomy, and if an emergency called for it, he invited them, their sisters, and their mother to accompany him on patient calls. "We came along in medicine like boys on a farm," Charlie later said. After earning their medical degrees—Will from the University of Michigan in 1883 and Charlie from Chicago Medical College five years later—they both returned to Rochester to join their father's growing practice.

On August 21, 1883, a devastating tornado swept through Rochester. The Mayos and other Rochester doctors soon established an emergency hospital in the town's dance hall. Recognizing the need for round-the-clock care for patients, the Mayos enlisted the help of Mother Mary Alfred Moes and the Sisters of St. Francis. Though trained as teachers, the nuns remained at the temporary hospital until it closed. Mother Alfred didn't forget her experience, though, and she began working with the Mayo family to establish a permanent hospital in Rochester. In 1889, St. Mary's Hospital, a three-story brick building equipped for twenty-seven patients, opened. The Mayo Clinic opened there in 1914.

The practices that make Mayo Clinic an international name today were established in the early years. Teamwork—groups of specialists working together to teach, to learn, and to treat patients—is at the heart of the clinic's practice of integrated care. Dr. Henry Plummer, who joined the clinic 1901, established other innovations. Credited with operating the clinic's first X-ray machine, Plummer was also the architect of the system of patient record keeping—in which each patient is assigned a number and a unique medical history chart—that is the foundation of today's record systems.

Dr. William J. (Will) Mayo said in 1910: "The sum-total of medical knowledge is now so great and wide-spreading that it would be futile for one man to attempt to acquire, or for any one man to assume that he has, even a good working knowledge of any large part of the whole...The best interest of the patient is the only interest to be considered, and in order that the sick may have the benefit of advancing knowledge, union of forces is necessary."

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Roberts, Kate. "Mayo Clinic." MNopedia, Minnesota Historical Society. https://www3.mnhs.org/mnopedia/search/index/group/mayo-clinic
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First Published: June 28, 2011
Last Modified: April 11, 2025

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Related Images

Mayo Clinic, Rochester

Mayo Clinic, Rochester, c.1930.

Louise Wright Mayo, wife of Dr. William W. Mayo

Louise Wright Mayo, wife of Dr. William W. Mayo, c.1860. Photographer: Easton's Photograph Gallery.

First Mayo Clinic Office, Rochester

First Mayo Clinic office, Rochester, 1883.

Dr. William W. Mayo

Dr. William W. Mayo, c.1900.

Drs. Charles Horace Mayo and William James Mayo

Drs. Charles H. Mayo and William J. Mayo in the first operating room at St. Mary's Hospital, Rochester, 1904.

William J. Mayo, William W. Mayo, Charles H. Mayo

William J. Mayo, William W. Mayo, and Charles H. Mayo, c.1910.

Second Mayo Clinic Office, Rochester

Second Mayo Clinic office, Rochester, 1911.

Dr. Charles Horace Mayo operating at the Mayo Clinic, Rochester

Dr. Charles H. Mayo operating at the Mayo Clinic, Rochester, 1913.

Black and white photograph of Mayo Clinic, Rochester, 1915.

Mayo Clinic, Rochester, c.1928.

Mayo Clinic, Rochester

Mayo Clinic, Rochester, c.1928.

Desk F at the Mayo Clinic, Rochester

Desk F at the Mayo Clinic, Rochester, 1933.

Dr. William J. Mayo

Dr. William J. Mayo, c.1933.

Dr. William J. Mayo and Dr. Charles H. Mayo with President Franklin Roosevelt

Dr. William J. Mayo and Dr. Charles H. Mayo with President Franklin Roosevelt, Rochester, 1934.

Dr. Charles H. Mayo

Dr. Charles H. Mayo, c.1935.

Statue of William and Charles Mayo, Mayo Park, Rochester

Statue of William and Charles Mayo, Mayo Park, Rochester, c.1952.

Aerial view, Mayo Clinic and surrounding area, Rochester

Aerial view, Mayo Clinic and surrounding area, Rochester, 1972. Photographer: Vincent H. Mart.

Mayo Clinic, Rochester

Mayo Clinic, Rochester

Mayo Clinic, Rochester, c.1930.

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Louise Wright Mayo, wife of Dr. William W. Mayo

Louise Wright Mayo, wife of Dr. William W. Mayo

Louise Wright Mayo, wife of Dr. William W. Mayo, c.1860. Photographer: Easton's Photograph Gallery.

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Minnesota Historical Society
First Mayo Clinic Office, Rochester

First Mayo Clinic Office, Rochester

First Mayo Clinic office, Rochester, 1883.

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Dr. William W. Mayo

Dr. William W. Mayo

Dr. William W. Mayo, c.1900.

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Minnesota Historical Society
Drs. Charles Horace Mayo and William James Mayo

Drs. Charles Horace Mayo and William James Mayo

Drs. Charles H. Mayo and William J. Mayo in the first operating room at St. Mary's Hospital, Rochester, 1904.

Public domain

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Minnesota Historical Society
William J. Mayo, William W. Mayo, Charles H. Mayo

William J. Mayo, William W. Mayo, Charles H. Mayo

William J. Mayo, William W. Mayo, and Charles H. Mayo, c.1910.

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Minnesota Historical Society
Second Mayo Clinic Office, Rochester

Second Mayo Clinic Office, Rochester

Second Mayo Clinic office, Rochester, 1911.

Public domain

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Minnesota Historical Society
Dr. Charles Horace Mayo operating at the Mayo Clinic, Rochester

Dr. Charles Horace Mayo operating at the Mayo Clinic, Rochester

Dr. Charles H. Mayo operating at the Mayo Clinic, Rochester, 1913.

Public domain

Black and white photograph of Mayo Clinic, Rochester, 1915.

Mayo Clinic, Rochester

Mayo Clinic, Rochester, c.1928.

Public domain

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Minnesota Historical Society
Mayo Clinic, Rochester

Mayo Clinic, Rochester

Mayo Clinic, Rochester, c.1928.

Desk F at the Mayo Clinic, Rochester

Desk F at the Mayo Clinic, Rochester

Desk F at the Mayo Clinic, Rochester, 1933.

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Minnesota Historical Society
Dr. William J. Mayo

Dr. William J. Mayo

Dr. William J. Mayo, c.1933.

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Minnesota Historical Society
Dr. William J. Mayo and Dr. Charles H. Mayo with President Franklin Roosevelt

Dr. William J. Mayo and Dr. Charles H. Mayo with President Franklin Roosevelt

Dr. William J. Mayo and Dr. Charles H. Mayo with President Franklin Roosevelt, Rochester, 1934.

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Minnesota Historical Society
Dr. Charles H. Mayo

Dr. Charles H. Mayo

Dr. Charles H. Mayo, c.1935.

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Minnesota Historical Society
Statue of William and Charles Mayo, Mayo Park, Rochester

Statue of William and Charles Mayo, Mayo Park, Rochester

Statue of William and Charles Mayo, Mayo Park, Rochester, c.1952.

Holding Location

Minnesota Historical Society
Aerial view, Mayo Clinic and surrounding area, Rochester

Aerial view, Mayo Clinic and surrounding area, Rochester

Aerial view, Mayo Clinic and surrounding area, Rochester, 1972. Photographer: Vincent H. Mart.

Holding Location

Minnesota Historical Society

Turning Point

In 1883, the Doctors Mayo, along with other Rochester doctors, establish an emergency hospital following a devastating August tornado. This act eventually leads to the founding of the world-renowned Mayo Clinic.

Chronology

1819
William Worrall Mayo is born on May 31 in a small village near Manchester, England.
1850
William W. Mayo completes his medical training in Indiana.
1861
William W. Mayo, living in Le Sueur, Minnesota, volunteers for duty in the Union army, but his application for regimental surgeon is denied.
1864
William W. Mayo, his wife Louise, and their children settle down in Rochester, Minnesota.
1883
William J. Mayo earns his medical degree from the University of Michigan. Soon after, Charles H. Mayo earns his medical degree from Chicago Medical College. They both return to Rochester to join their father's growing practice.
1889
St. Mary's Hospital, a three-story brick building equipped for twenty-seven patients, opens. The Mayo Clinic opens there in 1914.
1901
Dr. Henry Plummer joins Mayo Clinic and goes on to establish innovations in patient record keeping and more.

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